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Idea#108

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CKD »

Obesity and CKD

The mechanisms by which obesity and metabolic syndrome influence kidney function has not been well elucidated. Studies to investigate potential pathways are needed

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Submitted by 4 years ago

Comments (3)

  1. Is insulin resistance an underlying mechanism for endothelial dysfunction in the kidney and other microcirculatory beds?

    4 years ago
  2. I agree. The prevalence of obesity has substantially increased in the past decade. There are likely non-diabetes and non-hypertension mediated mechanisms of kidney injury in obesity. Interventional studies that target these mechanisms are warranted.

    4 years ago
  3. A lot might be learned from studying the implantation biopsies of living kidney donors. Obesity is not uncommon in this population.

    3 years ago

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