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Idea#108

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CKD »

Obesity and CKD

The mechanisms by which obesity and metabolic syndrome influence kidney function has not been well elucidated. Studies to investigate potential pathways are needed

Comment

Submitted by Richard Johnson 3 years ago

Comments (3)

  1. Is insulin resistance an underlying mechanism for endothelial dysfunction in the kidney and other microcirculatory beds?

    3 years ago
  2. I agree. The prevalence of obesity has substantially increased in the past decade. There are likely non-diabetes and non-hypertension mediated mechanisms of kidney injury in obesity. Interventional studies that target these mechanisms are warranted.

    3 years ago
  3. A lot might be learned from studying the implantation biopsies of living kidney donors. Obesity is not uncommon in this population.

    3 years ago

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